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This rich and savory Deep Hamburger Sausage Pepperoni Pie combines all the indulgent flavors of a pizza with the comforting layers of a deep-dish pie. It has quickly become a go-to for hearty family dinners, especially when we crave something both fancy yet familiar.
I created this dish on a whim for a Friday movie night. Since then, it’s become a family tradition every couple of weeks!
- For the Crust:1 box ready-made pie crust (2 crusts) – Perfect for saving time without compromising on texture
- Butter:3 tablespoons melted – Helps create a golden, crisp crust when brushed on top
- Garlic Powder:½ teaspoon – Infuses the crust with aromatic savory flavor
- For the Filling:½ pound ground beef – Adds heartiness and structure while layering bold flavors
- Italian Sausage:½ pound, casings removed – Brings a mildly spiced, authentic kick
- Pepperoni:1 cup slices, divided – Signature pizza flavor; use high-quality pepperoni for less grease
- Mozzarella Cheese:2 cups shredded, divided – Essential for gooey layers
- Cheddar/Provolone Cheese:1 cup shredded – Adds richness and variation to the cheese profile
- Pizza Sauce/Marinara:1½ cups – Forms the saucy, tangy base with fresh tomato notes
- Italian Seasoning:1 teaspoon – Provides the iconic herbaceous flavor
- Garlic Powder:½ teaspoon – Heightens the savory aromas
- Red Pepper Flakes:½ teaspoon (optional) – Adds heat and balances the richness
How To Make Deep Hamburger Sausage Pepperoni Pie

I especially love the pepperoni’s crispy edges as they bake in the pie—it reminds me of my favorite pizza slice from family pizzeria visits.
Storage Tips
Allow leftovers to cool completely and store them in an airtight container for up to three days in the refrigerator. Reheat slices in the oven for the best texture to maintain the crust’s flakiness.
Ingredient Substitutions
Try turkey sausage or soy-based crumbles for a lighter or plant-based spin. Swap out pepperoni for mushrooms to reduce the salt levels while keeping texture intact.
Serving Suggestions
Pair this hearty pie with a simple green salad or garlic bread for a balanced yet comforting meal. A side of roasted vegetables also complements the richness beautifully.

This Deep Hamburger Sausage Pepperoni Pie transforms pizza night into something extra special. Full of comforting layers, it’s sure to become a family favorite. Enjoy every gooey, flaky, and savory bite!
Recommended Recipes
- Pair this recipe with our crowd-pleasing Garlic Chicken with Vegetables.
- For a comforting variation, see our Cheesy Chicken Broccoli Rice.
- Complete your meal with our sweet and savory Bear Style Tomato Spaghetti.
Recipe FAQs
Yes, you can assemble the pie a day ahead, cover it tightly, and refrigerate. Bake it fresh when ready to serve.
You can make a homemade pie crust using a simple flour, butter, and water dough. It adds a personal touch to the dish!
Absolutely! Replace the beef and sausage with plant-based alternatives or a mix of mushrooms and lentils for a flavorful vegetarian twist.
Aside from mozzarella and provolone, you can use Monterey Jack, Parmesan, or a smoky gouda for additional depth of flavor.
Brush the bottom crust with melted butter or lightly bake it for a few minutes before adding the filling to keep it crisp.
